Movie Poster
The Substance
If you follow the instructions, what could go wrong?
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
  • Released on 09/07/2024 (Movie)
  • 7.228 out of 10 (2676 votes on TMDB)
  • Horror / Science Fiction
  • Cast
  • Crew
Where to Watch
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Headshot of Demi Moore
Demi Moore

Character's name: "Elisabeth"
Birthday: 11/11/1962
Birthplace: Roswell, New Mexico, USA
Biography:
Demi Moore (born Demetria Gene Guynes) is an American actress and film producer. After making her film debut in 1981, she appeared on the soap opera General Hospital and subsequently gained recognition as a member of the Brat Pack with roles in Blame It on Rio (1984), St. Elmo's Fire (1985), and About Last Night... (1986). Her starring role in Ghost (1990), the highest-grossing film of that year, earned her a Golden Globe nomination. She had further box-office success in the early 1990s, with the films A Few Good Men (1992), Indecent Proposal (1993), and Disclosure (1994). She portrayed Claire Donnelly in the drama film If These Walls Could Talk (1996), for which she was nominated for a Golden Globe Award and a Primetime Emmy Award. In 1996, Moore became the highest-paid actress in film history when she received an unprecedented $12.5 million salary to star in Striptease. She voiced the role of Esmeralda in The Hunchback of Notre Dame (1996) and The Hunchback of Notre Dame II (2002). Her next major role, G.I. Jane (1997), for which she shaved her head, was followed by a lengthy hiatus. She achieved further success in the following decades with the films Charlie's Angels: Full Throttle (2003), Bobby (2006), Mr. Brooks (2007), Margin Call (2011), and Rough Night (2017). In 2019, Moore released a memoir titled Inside Out, which instantly became a New York Times Best Seller.

Headshot of Margaret Qualley
Margaret Qualley

Character's name: "Sue"
Birthday: 10/23/1994
Birthplace: Kalispell, Montana, USA
Biography:
Sarah Margaret Qualley (born October 23, 1994) is an American actress. The daughter of actress Andie MacDowell, she trained as a ballerina in her youth and briefly pursued a career in modeling. She made her acting debut with a minor role in the 2013 drama film Palo Alto and gained recognition for playing a troubled teenager in the HBO drama series The Leftovers (2014–2017). Qualley then appeared in the dark comedy The Nice Guys (2016) and in Netflix's supernatural thriller Death Note (2017). Qualley gained acclaim and a nomination for a Primetime Emmy Award for portraying actress and dancer Ann Reinking in the FX biographical drama miniseries Fosse/Verdon (2019) and the title role in the Netflix drama miniseries Maid (2021). Her biggest commercial success came with Quentin Tarantino's comedy-drama Once Upon a Time in Hollywood (2019).

Headshot of Dennis Quaid
Dennis Quaid

Character's name: "Harvey"
Birthday: 04/09/1954
Birthplace: Houston, Texas, USA
Biography:
Dennis William Quaid (born April 9, 1954) is an American actor. He became known during the 1980s after appearing in several successful films, including as Mike Brody in Jaws 3-D (1983), Alex Gardner in Dreamscape (1984), Remy McSwain in The Big Easy (1987), Tuck Pendleton in Innerspace (1987), Jefferson "Jeff" Blue in Undercover Blues (1993), Bowen in Dragonheart (1996), Joe Doe/William in Gang Related (1997), Frank Towns in Flight of the Phoenix (2004), Jack Hall in The Day After Tomorrow (2004) and Reverend Shaw Moore in Footloose (2011).

Headshot of Edward Hamilton-Clark
Edward Hamilton-Clark

Character's name: "Fred"
Birthday: 12/22/2024
Biography:
Edward Hamilton-Clark is a Canadian actor who provided the motion capture for Ash and the voice for Glenn Sanders in Heavy Rain. He has also had roles in movies, TV series, and video games such as Bon voyage and Female Agents.

Headshot of Gore Abrams
Gore Abrams

Character's name: "Oliver"
Birthday: 12/22/2024

Headshot of Oscar Lesage
Oscar Lesage

Character's name: "Troy"
Birthday: 12/22/2024

Headshot of Christian Erickson
Christian Erickson

Character's name: "Man at Diner"
Birthday: 12/22/2024
Biography:
Christian Erickson is an American actor based in Paris, France. He is known for his role as General Kormarov in the film adaption of Hitman and as Lance Boyle, the TV presenter in the MegaRace video games series. Source: Article "Christian Erickson" from Wikipedia in English, licensed under CC-BY-SA 3.0.

Headshot of Robin Greer
Robin Greer

Character's name: "Male Nurse"
Birthday: 12/22/2024

Headshot of Tom Morton
Tom Morton

Character's name: "Doctor"
Birthday: 07/29/1981
Birthplace: London, England, UK
Biography:
Tom Morton is an English actor, born in London and educated at the French Lycee there. He studied History and Languages at the University of Edinburgh where he also got involved in the Bedlam Theatre, the university's student theatre company. After completing his degree he returned to London before moving to Paris in 2004. He attended the Cours Florent for two years and was cast in his first feature role in 2006, playing opposite Michele Laroque and Jacques Gamblin in the second film by Isabelle Mergault, director of the award-winning Je Vous Trouve Tres Beau.

Headshot of Hugo Diego Garcia
Hugo Diego Garcia

Character's name: "Diego - Boyfriend"
Birthday: 12/22/2024

Headshot of Daniel Knight
Daniel Knight

Character's name: "Casting Director"
Birthday: 12/22/2024

Headshot of Jonathon Carley
Jonathon Carley

Character's name: "Assistant Casting Director"
Birthday: 12/22/2024

Headshot of Jiselle Henderkott
Jiselle Henderkott

Character's name: "Girl Auditioning / New Year's Eve Show Dancer"
Birthday: 12/22/2024

Headshot of Akil Wingate
Akil Wingate

Character's name: "TV Host"
Birthday: 12/22/2024

Headshot of Vincent Colombe
Vincent Colombe

Character's name: "Man in Suit #1 - Harvey's Office"
Birthday: 07/14/1972


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Erik Baiers
Executive Producer

Headshot of Coralie Fargeat
Coralie Fargeat
Director

Headshot of Eric Fellner
Eric Fellner
Producer

Headshot of Coralie Fargeat
Coralie Fargeat
Producer

Headshot of Tim Bevan
Tim Bevan
Producer

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Alexandra Loewy
Executive Producer

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Nicolas Royer
Executive Producer

Headshot of Coralie Fargeat
Coralie Fargeat
Writer

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