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The Substance
Become a better you.
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
  • Released on 09/07/2024 (Movie)
  • 7.1 out of 10 (3632 votes on TMDB)
  • Horror / Science Fiction
  • Cast
  • Crew
Where to Watch
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Headshot of Demi Moore
Demi Moore

Character's name: "Elisabeth"
Birthday: 11/11/1962
Birthplace: Roswell, New Mexico, USA
Biography:
Demi Gene Moore (/dəˈmiː/ də-MEE; née Guynes; born November 11, 1962) is an American actress. After rising to prominence in the early 1980s, Moore became the world's highest-paid actress in 1995. Her accolades include a Golden Globe Award and nominations for a British Academy Film Award, a Primetime Emmy Award and a Academy Award. Moore began her career as a model and joined the cast of the soap opera General Hospital in 1981. After departing the show in 1983, she rose to prominence as a member of the Brat Pack, with roles in the films Blame It on Rio (1984), St. Elmo's Fire (1985), and About Last Night... (1986). She emerged as a star with her portrayal of a grieving artist in the romance film Ghost (1990), had further box office success in A Few Good Men(1992), Indecent Proposal (1993), and Disclosure(1994), and received a then-unprecedented $12.5 million to star in Striptease (1996). Moore's output decreased significantly after The Scarlet Letter (1995), The Juror (1996), and G.I. Jane (1997) fell below commercial expectations. She has since held sporadic leading roles in arthouse films, supporting roles in Charlie's Angels: Full Throttle (2003), Bobby (2006), Mr. Brooks (2007), and Margin Call (2011), as well as television credits in If These Walls Could Talk(1996), Empire (2017–2018), and Feud: Capote vs. The Swans (2024). She received renewed critical recognition for her performance as an ageing celebrity in the body horror film The Substance (2024). Moore has been married three times. From 1981 to 1985, she was married to musician Freddy Moore. From 1987 to 2000, she was married to Bruce Willis, with whom she has three daughters. She was married to Ashton Kutcher from 2005 to 2013. Her memoir Inside Out(2019) became a New York Times Best Seller. Description above from the Wikipedia article Demi Moore, licensed under CC-BY-SA, full list of contributors on Wikipedia.

Headshot of Margaret Qualley
Margaret Qualley

Character's name: "Sue"
Birthday: 10/23/1994
Birthplace: Kalispell, Montana, USA
Biography:
Sarah Margaret Qualley (born October 23, 1994) is an American actress. The daughter of actress Andie MacDowell, she trained as a ballerina in her youth and briefly pursued a career in modeling. She made her acting debut with a minor role in the 2013 drama film Palo Alto and gained recognition for playing a troubled teenager in the HBO drama series The Leftovers (2014–2017). Qualley then appeared in the dark comedy The Nice Guys (2016) and in Netflix's supernatural thriller Death Note (2017). Qualley gained acclaim and a nomination for a Primetime Emmy Award for portraying actress and dancer Ann Reinking in the FX biographical drama miniseries Fosse/Verdon (2019) and the title role in the Netflix drama miniseries Maid (2021). Her biggest commercial success came with Quentin Tarantino's comedy-drama Once Upon a Time in Hollywood (2019).

Headshot of Dennis Quaid
Dennis Quaid

Character's name: "Harvey"
Birthday: 04/09/1954
Birthplace: Houston, Texas, USA
Biography:
Dennis William Quaid (born April 9, 1954) is an American actor. He became known during the 1980s after appearing in several successful films, including as Mike Brody in Jaws 3-D (1983), Alex Gardner in Dreamscape (1984), Remy McSwain in The Big Easy (1987), Tuck Pendleton in Innerspace (1987), Jefferson "Jeff" Blue in Undercover Blues (1993), Bowen in Dragonheart (1996), Joe Doe/William in Gang Related (1997), Frank Towns in Flight of the Phoenix (2004), Jack Hall in The Day After Tomorrow (2004) and Reverend Shaw Moore in Footloose (2011).

Headshot of Edward Hamilton-Clark
Edward Hamilton-Clark

Character's name: "Fred"
Birthday: 02/05/2025
Biography:
Edward Hamilton-Clark is a Canadian actor who provided the motion capture for Ash and the voice for Glenn Sanders in Heavy Rain. He has also had roles in movies, TV series, and video games such as Bon voyage and Female Agents.

Headshot of Gore Abrams
Gore Abrams

Character's name: "Oliver"
Birthday: 10/03/1986
Birthplace: USA

Headshot of Oscar Lesage
Oscar Lesage

Character's name: "Troy"
Birthday: 02/05/2025

Headshot of Christian Erickson
Christian Erickson

Character's name: "Man at Diner"
Birthday: 02/05/2025
Biography:
Christian Erickson is an American actor based in Paris, France. He is known for his role as General Kormarov in the film adaption of Hitman and as Lance Boyle, the TV presenter in the MegaRace video games series. Source: Article "Christian Erickson" from Wikipedia in English, licensed under CC-BY-SA 3.0.

Headshot of Robin Greer
Robin Greer

Character's name: "Male Nurse"
Birthday: 02/05/2025

Headshot of Tom Morton
Tom Morton

Character's name: "Doctor"
Birthday: 07/29/1981
Birthplace: London, England, UK
Biography:
Tom Morton is an English actor, born in London and educated at the French Lycee there. He studied History and Languages at the University of Edinburgh where he also got involved in the Bedlam Theatre, the university's student theatre company. After completing his degree he returned to London before moving to Paris in 2004. He attended the Cours Florent for two years and was cast in his first feature role in 2006, playing opposite Michele Laroque and Jacques Gamblin in the second film by Isabelle Mergault, director of the award-winning Je Vous Trouve Tres Beau.

Headshot of Hugo Diego Garcia
Hugo Diego Garcia

Character's name: "Diego - Boyfriend"
Birthday: 02/05/2025

Headshot of Daniel Knight
Daniel Knight

Character's name: "Casting Director"
Birthday: 02/05/2025

Headshot of Jonathon Carley
Jonathon Carley

Character's name: "Assistant Casting Director"
Birthday: 02/05/2025

Headshot of Jiselle Henderkott
Jiselle Henderkott

Character's name: "Girl Auditioning / New Year's Eve Show Dancer"
Birthday: 02/05/2025

Headshot of Akil Wingate
Akil Wingate

Character's name: "TV Host"
Birthday: 02/05/2025

Headshot of Vincent Colombe
Vincent Colombe

Character's name: "Man in Suit #1 - Harvey's Office"
Birthday: 07/14/1972


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Erik Baiers
Executive Producer

Headshot of Coralie Fargeat
Coralie Fargeat
Director

Headshot of Coralie Fargeat
Coralie Fargeat
Producer

Headshot of Eric Fellner
Eric Fellner
Producer

Headshot of Tim Bevan
Tim Bevan
Producer

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Alexandra Loewy
Executive Producer

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Nicolas Royer
Executive Producer

Headshot of Coralie Fargeat
Coralie Fargeat
Writer

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